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Identification of Substituted Amino Acid Hydrazides as Novel Anti-Tubercular Agents, Using a Scaffold Hopping Approach

Discovery and development of new therapeutic options for the treatment of Mycobacterium tuberculosis (Mtb) infection, particularly drug-resistant strains, are urgently required to tackle the global burden of this disease. Herein, we reported the synthesis of a novel series of N-substituted amino aci...

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Detalles Bibliográficos
Autores principales: Brown, Alistair K., Aljohani, Ahmed K. B., Alsalem, Fatimah M. A., Broadhead, Joseph L., Gill, Jason H., Lu, Yucheng, Sellars, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287914/
https://www.ncbi.nlm.nih.gov/pubmed/32455566
http://dx.doi.org/10.3390/molecules25102387