Cargando…
Identification of Substituted Amino Acid Hydrazides as Novel Anti-Tubercular Agents, Using a Scaffold Hopping Approach
Discovery and development of new therapeutic options for the treatment of Mycobacterium tuberculosis (Mtb) infection, particularly drug-resistant strains, are urgently required to tackle the global burden of this disease. Herein, we reported the synthesis of a novel series of N-substituted amino aci...
Autores principales: | Brown, Alistair K., Aljohani, Ahmed K. B., Alsalem, Fatimah M. A., Broadhead, Joseph L., Gill, Jason H., Lu, Yucheng, Sellars, Jonathan D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287914/ https://www.ncbi.nlm.nih.gov/pubmed/32455566 http://dx.doi.org/10.3390/molecules25102387 |
Ejemplares similares
-
Identification of Novel Benzoxa-[2,1,3]-diazole Substituted Amino Acid Hydrazides as Potential Anti-Tubercular Agents
por: Brown, Alistair K., et al.
Publicado: (2019) -
Synthesis Biological Activity of Novel Amino Acid-(N′-Benzoyl) Hydrazide and Amino Acid-(N′-Nicotinoyl) Hydrazide Derivatives
por: Khattab, Sherine N.
Publicado: (2005) -
Indole: A promising scaffold for the discovery and development of potential anti-tubercular agents
por: Bajad, Nilesh Gajanan, et al.
Publicado: (2022) -
In silico work flow for scaffold hopping in Leishmania
por: Waugh, Barnali, et al.
Publicado: (2014) -
Scaffold Hopping Toward Agomelatine: Novel 3, 4-Dihydroisoquinoline Compounds as Potential Antidepressant Agents
por: Yang, Yang, et al.
Publicado: (2016)