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Modulating the Properties of Fe(III) Macrocyclic MRI Contrast Agents by Appending Sulfonate or Hydroxyl Groups

Complexes of Fe(III) that contain a triazacyclononane (TACN) macrocycle, two pendant hydroxyl groups, and a third ancillary pendant show promise as MRI contrast agents. The ancillary group plays an important role in tuning the solution relaxivity of the Fe(III) complex and leads to large changes in...

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Detalles Bibliográficos
Autores principales: Asik, Didar, Smolinski, Rachel, Abozeid, Samira M., Mitchell, Travis B., Turowski, Steven G., Spernyak, Joseph A., Morrow, Janet R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288058/
https://www.ncbi.nlm.nih.gov/pubmed/32414058
http://dx.doi.org/10.3390/molecules25102291