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Mechanisms Regulating the UPS-ALS Crosstalk: The Role of Proteaphagy

Protein degradation is tightly regulated inside cells because of its utmost importance for protein homeostasis (proteostasis). The two major intracellular proteolytic pathways are the ubiquitin-proteasome and the autophagy-lysosome systems which ensure the fate of proteins when modified by various m...

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Detalles Bibliográficos
Autores principales: Quinet, Grégoire, Gonzalez-Santamarta, Maria, Louche, Clara, Rodriguez, Manuel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288101/
https://www.ncbi.nlm.nih.gov/pubmed/32443527
http://dx.doi.org/10.3390/molecules25102352