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Mechanisms Regulating the UPS-ALS Crosstalk: The Role of Proteaphagy
Protein degradation is tightly regulated inside cells because of its utmost importance for protein homeostasis (proteostasis). The two major intracellular proteolytic pathways are the ubiquitin-proteasome and the autophagy-lysosome systems which ensure the fate of proteins when modified by various m...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288101/ https://www.ncbi.nlm.nih.gov/pubmed/32443527 http://dx.doi.org/10.3390/molecules25102352 |