Discovery of a Natural Product That Binds to the Mycobacterium tuberculosis Protein Rv1466 Using Native Mass Spectrometry

Elucidation of the mechanism of action of compounds with cellular bioactivity is important for progressing compounds into future drug development. In recent years, phenotype-based drug discovery has become the dominant approach to drug discovery over target-based drug discovery, which relies on the...

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Detalles Bibliográficos
Autores principales: Elnaas, Ali R., Grice, Darren, Han, Jianying, Feng, Yunjiang, Capua, Angela Di, Mak, Tin, Laureanti, Joseph A., Buchko, Garry W., Myler, Peter J., Cook, Gregory, Quinn, Ronald J., Liu, Miaomiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288112/
https://www.ncbi.nlm.nih.gov/pubmed/32455540
http://dx.doi.org/10.3390/molecules25102384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288112/
https://www.ncbi.nlm.nih.gov/pubmed/32455540
http://dx.doi.org/10.3390/molecules25102384

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