1,2,4-Triazine Sulfonamides: Synthesis by Sulfenamide Intermediates, In Vitro Anticancer Screening, Structural Characterization, and Molecular Docking Study

In this study, we synthesized novel sulfonamides with a 1,2,4-triazine moiety according to pharmacophore requirements for biological activity. All the synthesized compounds were tested in vitro to verify whether they exhibited anticancer activity against the human breast cancer cell lines MCF-7 and...

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Detalles Bibliográficos
Autores principales: Branowska, Danuta, Karczmarzyk, Zbigniew, Wolińska, Ewa, Wysocki, Waldemar, Morawiak, Maja, Urbańczyk-Lipkowska, Zofia, Bielawska, Anna, Bielawski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288137/
https://www.ncbi.nlm.nih.gov/pubmed/32429377
http://dx.doi.org/10.3390/molecules25102324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288137/
https://www.ncbi.nlm.nih.gov/pubmed/32429377
http://dx.doi.org/10.3390/molecules25102324

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