Development of Novel Analogs of the Monocarboxylate Transporter Ligand FACH and Biological Validation of One Potential Radiotracer for Positron Emission Tomography (PET) Imaging

Monocarboxylate transporters 1-4 (MCT1-4) are involved in several metabolism-related diseases, especially cancer, providing the chance to be considered as relevant targets for diagnosis and therapy. [(18)F]FACH was recently developed and showed very promising preclinical results as a potential posit...

Descripción completa

Detalles Bibliográficos
Autores principales: Sadeghzadeh, Masoud, Wenzel, Barbara, Gündel, Daniel, Deuther-Conrad, Winnie, Toussaint, Magali, Moldovan, Rareş-Petru, Fischer, Steffen, Ludwig, Friedrich-Alexander, Teodoro, Rodrigo, Jonnalagadda, Shirisha, Jonnalagadda, Sravan K., Schüürmann, Gerrit, Mereddy, Venkatram R., Drewes, Lester R., Brust, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288138/
https://www.ncbi.nlm.nih.gov/pubmed/32423056
http://dx.doi.org/10.3390/molecules25102309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288138/
https://www.ncbi.nlm.nih.gov/pubmed/32423056
http://dx.doi.org/10.3390/molecules25102309

Ejemplares similares