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Synthesis and Cytotoxic Activity of Chiral Sulfonamides Based on the 2-Azabicycloalkane Skeleton

A series of chiral sulfonamides containing the 2-azabicycloalkane scaffold were prepared from aza-Diels–Alder cycloadducts through their conversion to amines based on 2-azanorbornane or the bridged azepane skeleton, followed by the reaction with sulfonyl chlorides. The cytotoxic activity of the obta...

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Detalles Bibliográficos
Autores principales: Samadaei, Mahzeiar, Pinter, Matthias, Senfter, Daniel, Madlener, Sibylle, Rohr-Udilova, Nataliya, Iwan, Dominika, Kamińska, Karolina, Wojaczyńska, Elżbieta, Wojaczyński, Jacek, Kochel, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288168/
https://www.ncbi.nlm.nih.gov/pubmed/32443610
http://dx.doi.org/10.3390/molecules25102355