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From threat to cure: understanding of virus-induced cell death leads to highly immunogenic oncolytic influenza viruses

Oncolytic viruses constitute an emerging strategy in immunomodulatory cancer treatment. The first oncolytic virus, Talimogene laherparepvec (T-VEC), based on herpes simplex virus 1 (HSV-1), was approved by the Food and Drug Administration (FDA) and European Medicines Agency (EMA) in 2015. The field...

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Detalles Bibliográficos
Autores principales: Kabiljo, Julijan, Laengle, Johannes, Bergmann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288254/
https://www.ncbi.nlm.nih.gov/pubmed/32542113
http://dx.doi.org/10.1038/s41420-020-0284-1