Inhibition of Protein-Tyrosine Phosphatase PTP1B and LMPTP Promotes Palmitate/Oleate-Challenged HepG2 Cell Survival by Reducing Lipoapoptosis, Improving Mitochondrial Dynamics and Mitigating Oxidative and Endoplasmic Reticulum Stress

Objectives: Non-alcoholic fatty liver disease (NAFLD) is considered a well-known pathology that is determined without using alcohol and has emerged as a growing public health problem. Lipotoxicity is known to promote hepatocyte death, which, in the context of NAFLD, is termed lipoapoptosis. The seve...

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Detalles Bibliográficos
Autores principales: Bourebaba, Lynda, Łyczko, Jacek, Alicka, Michalina, Bourebaba, Nabila, Szumny, Antoni, Fal, Andrzej M., Marycz, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288314/
https://www.ncbi.nlm.nih.gov/pubmed/32369900
http://dx.doi.org/10.3390/jcm9051294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288314/
https://www.ncbi.nlm.nih.gov/pubmed/32369900
http://dx.doi.org/10.3390/jcm9051294

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