Histone Deacetylases (HDACs): Evolution, Specificity, Role in Transcriptional Complexes, and Pharmacological Actionability

Histone deacetylases (HDACs) are evolutionary conserved enzymes which operate by removing acetyl groups from histones and other protein regulatory factors, with functional consequences on chromatin remodeling and gene expression profiles. We provide here a review on the recent knowledge accrued on t...

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Detalles Bibliográficos
Autores principales: Milazzo, Giorgio, Mercatelli, Daniele, Di Muzio, Giulia, Triboli, Luca, De Rosa, Piergiuseppe, Perini, Giovanni, Giorgi, Federico M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288346/
https://www.ncbi.nlm.nih.gov/pubmed/32429325
http://dx.doi.org/10.3390/genes11050556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288346/
https://www.ncbi.nlm.nih.gov/pubmed/32429325
http://dx.doi.org/10.3390/genes11050556

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