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Mass Spectrometric Imaging of the Brain Demonstrates the Regional Displacement of 6-Monoacetylmorphine by Naloxone

[Image: see text] Overdose is the main cause of mortality among heroin users. Many of these overdose-induced deaths can be prevented through the timely administration of naloxone (NLX), a nonselective mu (μ)-, kappa (κ)-, and delta (δ)-opioid receptor antagonist. NLX competitively inhibits opioid-ov...

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Detalles Bibliográficos
Autores principales: Teklezgi, Belin G., Pamreddy, Annapurna, Ntshangase, Sphamandla, Mdanda, Sipho, Singh, Sanil D., Gopal, Nirmala D., Naicker, Tricia, Kruger, Hendrik G., Govender, Thavendran, Baijnath, Sooraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288357/
https://www.ncbi.nlm.nih.gov/pubmed/32548443
http://dx.doi.org/10.1021/acsomega.9b03570