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Mass Spectrometric Imaging of the Brain Demonstrates the Regional Displacement of 6-Monoacetylmorphine by Naloxone
[Image: see text] Overdose is the main cause of mortality among heroin users. Many of these overdose-induced deaths can be prevented through the timely administration of naloxone (NLX), a nonselective mu (μ)-, kappa (κ)-, and delta (δ)-opioid receptor antagonist. NLX competitively inhibits opioid-ov...
Autores principales: | Teklezgi, Belin G., Pamreddy, Annapurna, Ntshangase, Sphamandla, Mdanda, Sipho, Singh, Sanil D., Gopal, Nirmala D., Naicker, Tricia, Kruger, Hendrik G., Govender, Thavendran, Baijnath, Sooraj |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288357/ https://www.ncbi.nlm.nih.gov/pubmed/32548443 http://dx.doi.org/10.1021/acsomega.9b03570 |
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