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Diverse LEF/TCF Expression in Human Colorectal Cancer Correlates with Altered Wnt-Regulated Transcriptome in a Meta-Analysis of Patient Biopsies

Aberrantly activated Wnt signaling causes cellular transformation that can lead to human colorectal cancer. Wnt signaling is mediated by Lymphoid Enhancer Factor/T-Cell Factor (LEF/TCF) DNA-binding factors. Here we investigate whether altered LEF/TCF expression is conserved in human colorectal tumor...

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Detalles Bibliográficos
Autores principales: Mayer, Claus-Dieter, Magon de La Giclais, Soizick, Alsehly, Fozan, Hoppler, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288467/
https://www.ncbi.nlm.nih.gov/pubmed/32403323
http://dx.doi.org/10.3390/genes11050538