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Diverse LEF/TCF Expression in Human Colorectal Cancer Correlates with Altered Wnt-Regulated Transcriptome in a Meta-Analysis of Patient Biopsies

Aberrantly activated Wnt signaling causes cellular transformation that can lead to human colorectal cancer. Wnt signaling is mediated by Lymphoid Enhancer Factor/T-Cell Factor (LEF/TCF) DNA-binding factors. Here we investigate whether altered LEF/TCF expression is conserved in human colorectal tumor...

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Detalles Bibliográficos
Autores principales:	Mayer, Claus-Dieter, Magon de La Giclais, Soizick, Alsehly, Fozan, Hoppler, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288467/ https://www.ncbi.nlm.nih.gov/pubmed/32403323 http://dx.doi.org/10.3390/genes11050538

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