Development of human prostate cancer stem cells involves epigenomic alteration and PI3K/AKT pathway activation

BACKGROUND: Human prostate cancer spheres endowed with stem cell properties have been obtained from androgen-dependent cell line LNCaP after exposure to an epigenomic modulator phenethyl isothiocynate (PEITC). Sphere cells can self-renew and grow with androgen, and also without androgen. Little is k...

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Detalles Bibliográficos
Autores principales: Wu, Jingjing, Cang, Shundong, Liu, Christina, Ochiai, Whitman, Chiao, Jen Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288500/
https://www.ncbi.nlm.nih.gov/pubmed/32537260
http://dx.doi.org/10.1186/s40164-020-00168-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288500/
https://www.ncbi.nlm.nih.gov/pubmed/32537260
http://dx.doi.org/10.1186/s40164-020-00168-0

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