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A Luminescence-Based System for Identification of Genetically Encodable Inhibitors of Protein Aggregation

[Image: see text] Molecules that disrupt protein aggregation represent potential tool compounds for the investigation of numerous human disease states. However, the identification of small molecules capable of disrupting protein aggregation has proven challenging. Larger biomolecules such as antibod...

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Detalles Bibliográficos
Autores principales: Nelson, Travis J., Liang, Shuo, Stains, Cliff I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288563/
https://www.ncbi.nlm.nih.gov/pubmed/32548481
http://dx.doi.org/10.1021/acsomega.0c00779