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Antitumor Activity of Larotrectinib in Esophageal Carcinoma with NTRK Gene Amplification

BACKGROUND: Increasing knowledge about the genomic changes underpinning cancer development and growth has led to a rapidly expanding number of individualized therapies that specifically target these changes in a patient's tumor. Here we present a case report of a patient with metastatic esophag...

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Detalles Bibliográficos
Autores principales: Hempel, Dirk, Wieland, Thomas, Solfrank, Beate, Grossmann, Vera, Steinhard, Johanna, Frick, Andrea, Hempel, Louisa, Eberl, Thomas, Gaumann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288663/
https://www.ncbi.nlm.nih.gov/pubmed/32323889
http://dx.doi.org/10.1634/theoncologist.2019-0641