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Reduced Monocytic Human Leukocyte Antigen-DR Expression Indicates Immunosuppression in Critically Ill COVID-19 Patients

BACKGROUND: The cellular immune system is of pivotal importance with regard to the response to severe infections. Monocytes/macrophages are considered key immune cells in infections and downregulation of the surface expression of monocytic human leukocyte antigen-DR (mHLA-DR) within the major histoc...

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Detalles Bibliográficos
Autores principales: Spinetti, Thibaud, Hirzel, Cedric, Fux, Michaela, Walti, Laura N., Schober, Patrick, Stueber, Frank, Luedi, Markus M., Schefold, Joerg C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkin 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288784/
https://www.ncbi.nlm.nih.gov/pubmed/32925314
http://dx.doi.org/10.1213/ANE.0000000000005044