Apelin enhances IL-1β expression in human synovial fibroblasts by inhibiting miR-144-3p through the PI3K and ERK pathways

Much data suggests intersecting activities between the adipokine apelin (APLN) and the pathologic processes of obesity and osteoarthritis (OA), with APLN modulating cartilage, synovium, bone, and various immune cell activities. The synovium plays an important role in the pathogenesis of OA. We inves...

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Detalles Bibliográficos
Autores principales: Chang, Ting-Kuo, Wang, Yu-Han, Kuo, Shu-Jui, Wang, Shih-Wei, Tsai, Chun-Hao, Fong, Yi-Chin, Wu, Nan-Lin, Liu, Shan-Chi, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288923/
https://www.ncbi.nlm.nih.gov/pubmed/32420902
http://dx.doi.org/10.18632/aging.103195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288923/
https://www.ncbi.nlm.nih.gov/pubmed/32420902
http://dx.doi.org/10.18632/aging.103195

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