Physiological and metabolic features of mice with CRISPR/Cas9-mediated loss-of-function in growth hormone-releasing hormone

Our previous study demonstrated that the loss of growth hormone releasing hormone (GHRH) results in increased lifespan and improved metabolic homeostasis in the mouse model generated by classical embryonic stem cell-based gene-targeting method. In this study, we targeted the GHRH gene using the CRIS...

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Detalles Bibliográficos
Autores principales: Icyuz, Mert, Fitch, Michael, Zhang, Fang, Challa, Anil, Sun, Liou Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288930/
https://www.ncbi.nlm.nih.gov/pubmed/32422607
http://dx.doi.org/10.18632/aging.103242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288930/
https://www.ncbi.nlm.nih.gov/pubmed/32422607
http://dx.doi.org/10.18632/aging.103242

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