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Clioquinol improves motor and non-motor deficits in MPTP-induced monkey model of Parkinson’s disease through AKT/mTOR pathway

Despite decades of research into the pathology mechanisms of Parkinson’s disease (PD), disease-modifying therapy of PD is scarce. Thus, searching for new drugs or more effective neurosurgical treatments has elicited much interest. Clioquinol (CQ) has been shown to have therapeutic benefits in rodent...

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Detalles Bibliográficos
Autores principales: Shi, Liangqin, Huang, Chao, Luo, Qihui, Xia, Yu, Liu, Wentao, Zeng, Wen, Cheng, Anchun, Shi, Riyi, Zhengli, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288933/
https://www.ncbi.nlm.nih.gov/pubmed/32424108
http://dx.doi.org/10.18632/aging.103225