Dexmedetomidine inhibits LPS-induced proinflammatory responses via suppressing HIF1α-dependent glycolysis in macrophages

Dexmedetomidine, a highly selective α2-adrenoceptor agonist, has been reported to exert an anti-inflammatory effect in several animal models, but the mechanism remains unclear. Previous studies have shown that hypoxia inducible factor 1α-induced glycolysis is essential for the activation of inflamma...

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Detalles Bibliográficos
Autores principales: Meng, Qingyuan, Guo, Pinhao, Jiang, Zhengyu, Bo, Lulong, Bian, Jinjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288940/
https://www.ncbi.nlm.nih.gov/pubmed/32433037
http://dx.doi.org/10.18632/aging.103226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288940/
https://www.ncbi.nlm.nih.gov/pubmed/32433037
http://dx.doi.org/10.18632/aging.103226

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