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NF2 deficiency accelerates neointima hyperplasia following vascular injury via promoting YAP-TEAD1 interaction in vascular smooth muscle cells

Neurofibromin 2 (NF2), a potent tumor suppressor, is reported to inhibit proliferation in several cell types. The role of NF2 in neointima hyperplasia after vascular injury is unknown. We explored the role of NF2 in proliferation, migration of vascular smooth muscle cell (VSMC) and neointima hyperpl...

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Detalles Bibliográficos
Autores principales: Sun, Xiongshan, Li, Shuang, Gan, Xueqing, Chen, Ken, Yang, Dachun, Yang, Yongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288949/
https://www.ncbi.nlm.nih.gov/pubmed/32422606
http://dx.doi.org/10.18632/aging.103240