Klotho alleviates indoxyl sulfate-induced heart failure and kidney damage by promoting M2 macrophage polarization

Indoxyl sulfate (IS) is a protein-bound uremic toxin that can accumulate in patients with chronic kidney disease (CKD) or acute kidney injury (AKI) and cause kidney and cardiac dysfunction. Klotho is an anti-aging protein that has reno- and cardio-protective effects. We investigated whether Klotho c...

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Detalles Bibliográficos
Autores principales: Lv, Jing, Chen, Jin, Wang, Minjia, Yan, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288965/
https://www.ncbi.nlm.nih.gov/pubmed/32464602
http://dx.doi.org/10.18632/aging.103183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288965/
https://www.ncbi.nlm.nih.gov/pubmed/32464602
http://dx.doi.org/10.18632/aging.103183

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