Pyrrolo [3,4-b]-quinolin-9-amine compound FZU-0038-056 suppresses triple-negative breast cancer partially through inhibiting the expression of Bcl-2

Triple-negative breast cancer (TNBC) has a poorer prognosis than other subtypes of breast cancer; however, it lacks effective targeted therapies clinically. In this study, we found FZU-0038-056, a novel compound derived from last-stage functionalization of tetrahydro-β-carboline scaffold, showed the...

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Detalles Bibliográficos
Autores principales: Wang, Danping, Nie, Zhi, Jiang, Xiaoyan, Ye, Jinxiang, Wei, Zhimin, Cheng, Dating, Wang, Chenyang, Wu, Yingying, Liu, Rong, Chen, Haijun, Chen, Ceshi, Wang, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288966/
https://www.ncbi.nlm.nih.gov/pubmed/32452831
http://dx.doi.org/10.18632/aging.103232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288966/
https://www.ncbi.nlm.nih.gov/pubmed/32452831
http://dx.doi.org/10.18632/aging.103232

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