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Pyrrolo [3,4-b]-quinolin-9-amine compound FZU-0038-056 suppresses triple-negative breast cancer partially through inhibiting the expression of Bcl-2
Triple-negative breast cancer (TNBC) has a poorer prognosis than other subtypes of breast cancer; however, it lacks effective targeted therapies clinically. In this study, we found FZU-0038-056, a novel compound derived from last-stage functionalization of tetrahydro-β-carboline scaffold, showed the...
Autores principales: | Wang, Danping, Nie, Zhi, Jiang, Xiaoyan, Ye, Jinxiang, Wei, Zhimin, Cheng, Dating, Wang, Chenyang, Wu, Yingying, Liu, Rong, Chen, Haijun, Chen, Ceshi, Wang, Chunyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288966/ https://www.ncbi.nlm.nih.gov/pubmed/32452831 http://dx.doi.org/10.18632/aging.103232 |
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