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Muscle-dependent regulation of adipose tissue function in long-lived growth hormone-mutant mice

Altered adipose tissue may contribute to the longevity of Snell dwarf and growth hormone receptor (GHR) knock-out mice. We report here that white (WAT) and brown (BAT) fat have elevated UCP1 in both kinds of mice, and that adipocytes in WAT depots turn beige/brown. These imply increased thermogenesi...

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Detalles Bibliográficos
Autores principales: Li, Xinna, Frazier, Jacquelyn A., Spahiu, Edward, McPherson, Madaline, Miller, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288969/
https://www.ncbi.nlm.nih.gov/pubmed/32464603
http://dx.doi.org/10.18632/aging.103380