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A novel 3’,5’-diprenylated chalcone induces concurrent apoptosis and GSDME-dependent pyroptosis through activating PKCδ/JNK signal in prostate cancer

Although androgen deprivation therapy may initially be effective in prostate cancer, the disease can gradually progress to castration-resistant prostate cancer, at which point chemotherapy becomes the major clinical strategy. In this study, we demonstrated the anti-cancer potential of a novel 3’,5’-...

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Detalles Bibliográficos
Autores principales: Zhang, Yongqiang, Yang, Jue, Wen, Zhonghang, Chen, Xiaoyue, Yu, Jia, Yuan, Dongbo, Xu, Bixue, Luo, Heng, Zhu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288973/
https://www.ncbi.nlm.nih.gov/pubmed/32427575
http://dx.doi.org/10.18632/aging.103178