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Genome editing for blood disorders: state of the art and recent advances

In recent years, tremendous advances have been made in the use of gene editing to precisely engineer the genome. This technology relies on the activity of a wide range of nuclease platforms — such as zinc-finger nucleases, transcription activator-like effector nucleases, and the CRISPR–Cas system —...

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Detalles Bibliográficos
Autores principales: Romito, Marianna, Rai, Rajeev, Thrasher, Adrian J., Cavazza, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288986/
https://www.ncbi.nlm.nih.gov/pubmed/33523137
http://dx.doi.org/10.1042/ETLS20180147