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Mesenchymal traits at the convergence of tumor-intrinsic and -extrinsic mechanisms of resistance to immune checkpoint blockers

Targeting of immune checkpoint blockers (ICBs), such as cytotoxic T-lymphocyte antigen-4 and programmed-death 1/programmed-death ligand 1, has dramatically changed the landscape of cancer treatment. Seeing patients who were refractory to conventional therapy recover after immunotherapy, with high ra...

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Detalles Bibliográficos
Autores principales: Trono, Paola, Sistigu, Antonella, Palermo, Belinda, Ciliberto, Gennaro, Nisticò, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289012/
https://www.ncbi.nlm.nih.gov/pubmed/33525801
http://dx.doi.org/10.1042/ETLS20170068