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Sequence homology between human PARP14 and the SARS-CoV-2 ADP ribose 1’-phosphatase
• There is amino acid sequence homology between the ADP-ribose binding sites of human PARP14 and SARS-CoV-2 ADRP. • This homology is even more pronounced in bat species. • The model proposed highlights the potential of the PARP axis to yield druggable targets for the treatment of COVID-19.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
European Federation of Immunological Societies. Published by Elsevier B.V.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289111/ https://www.ncbi.nlm.nih.gov/pubmed/32534867 http://dx.doi.org/10.1016/j.imlet.2020.05.008 |