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1α, 25-dihydroxyvitamin D(3) inhibits transforming growth factor β1-induced epithelial-mesenchymal transition via β-catenin pathway

BACKGROUND: The transforming growth factor β1 (TGF-β1)-induced epithelial-mesenchymal transition (EMT) has been proven associated with the pathogenesis of asthmatic airway remodeling, in which the Wnt/β-catenin pathway plays an important role, notably with regard to TGF-β1. Recent studies have shown...

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Detalles Bibliográficos
Autores principales: Xiong, Xin-Rong, Tian, Xin-Li, Huo, Ru-Jie, Dong, Yan-Ting, Liu, Dai, Bai, Jing-Cui, Qi, Yun-Feng, Tian, Xin-Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289296/
https://www.ncbi.nlm.nih.gov/pubmed/32452895
http://dx.doi.org/10.1097/CM9.0000000000000830