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Amino Acid–Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet

Background: The chronic activation of the mechanistic (mammalian) target of rapamycin in complex 1 (mTORC1) in response to excess nutrients contributes to obesity-associated pathologies. Objective: To understand the initial events that ultimately lead to obesity-associated pathologies, the present s...

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Detalles Bibliográficos
Autores principales: Kimball, Scot R, Ravi, Suhana, Gordon, Bradley S, Dennis, Michael D, Jefferson, Leonard S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289329/
https://www.ncbi.nlm.nih.gov/pubmed/26400964
http://dx.doi.org/10.3945/jn.115.215491