Lowe syndrome patient fibroblasts display Ocrl1-specific cell migration defects that cannot be rescued by the homologous Inpp5b phosphatase

The Lowe syndrome (LS) is a life-threatening, developmental disease characterized by mental retardation, cataracts and renal failure. Although this human illness has been linked to defective function of the phosphatidylinositol 5-phosphatase, Ocrl1 (Oculo-Cerebro-Renal syndrome ofLowe protein1), the...

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Detalles Bibliográficos
Autores principales: Coon, Brian G., Mukherjee, Debarati, Hanna, Claudia B., Riese, David J., Lowe, Martin, Aguilar, R. Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289333/
https://www.ncbi.nlm.nih.gov/pubmed/19700499
http://dx.doi.org/10.1093/hmg/ddp407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289333/
https://www.ncbi.nlm.nih.gov/pubmed/19700499
http://dx.doi.org/10.1093/hmg/ddp407

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