Platelet activation via dynamic conformational changes of von Willebrand factor under shear

Shear-induced conformational changes of von Willebrand factor (VWF) play an important role in platelet activation. A novel approach describing VWF unfolding on the platelet surface under dynamic shear stress is proposed. Cumulative effect of dynamic shear on platelet activation via conformational ch...

Descripción completa

Detalles Bibliográficos
Autores principales: Pushin, Denis M., Salikhova, Tatiana Y., Zlobina, Ksenia E., Guria, Georgy Th.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289367/
https://www.ncbi.nlm.nih.gov/pubmed/32525962
http://dx.doi.org/10.1371/journal.pone.0234501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289367/
https://www.ncbi.nlm.nih.gov/pubmed/32525962
http://dx.doi.org/10.1371/journal.pone.0234501

Ejemplares similares