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Platelet activation via dynamic conformational changes of von Willebrand factor under shear

Shear-induced conformational changes of von Willebrand factor (VWF) play an important role in platelet activation. A novel approach describing VWF unfolding on the platelet surface under dynamic shear stress is proposed. Cumulative effect of dynamic shear on platelet activation via conformational ch...

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Detalles Bibliográficos
Autores principales:	Pushin, Denis M., Salikhova, Tatiana Y., Zlobina, Ksenia E., Guria, Georgy Th.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289367/ https://www.ncbi.nlm.nih.gov/pubmed/32525962 http://dx.doi.org/10.1371/journal.pone.0234501

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