Effects of Inorganic Arsenic on Human Prostate Stem-Progenitor Cell Transformation, Autophagic Flux Blockade, and NRF2 Pathway Activation

BACKGROUND: Inorganic arsenic (iAs) is an environmental toxicant associated with an increased risk of prostate cancer in chronically exposed populations worldwide. However, the biological mechanisms underlying iAs-induced prostate carcinogenesis remain unclear. OBJECTIVES: We studied how iAs affects...

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Detalles Bibliográficos
Autores principales: Xie, Lishi, Hu, Wen-Yang, Hu, Dan-Ping, Shi, Guangbin, Li, Ye, Yang, Jianfu, Prins, Gail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289393/
https://www.ncbi.nlm.nih.gov/pubmed/32525701
http://dx.doi.org/10.1289/EHP6471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289393/
https://www.ncbi.nlm.nih.gov/pubmed/32525701
http://dx.doi.org/10.1289/EHP6471

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