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Effects of Inorganic Arsenic on Human Prostate Stem-Progenitor Cell Transformation, Autophagic Flux Blockade, and NRF2 Pathway Activation
BACKGROUND: Inorganic arsenic (iAs) is an environmental toxicant associated with an increased risk of prostate cancer in chronically exposed populations worldwide. However, the biological mechanisms underlying iAs-induced prostate carcinogenesis remain unclear. OBJECTIVES: We studied how iAs affects...
Autores principales: | Xie, Lishi, Hu, Wen-Yang, Hu, Dan-Ping, Shi, Guangbin, Li, Ye, Yang, Jianfu, Prins, Gail S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Environmental Health Perspectives
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289393/ https://www.ncbi.nlm.nih.gov/pubmed/32525701 http://dx.doi.org/10.1289/EHP6471 |
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