Determination of metformin bio-distribution by LC-MS/MS in mice treated with a clinically relevant paradigm

Metformin, an anti-diabetes drug, has been recently emerging as a potential “anti-aging” intervention based on its reported beneficial actions against aging in preclinical studies. Nonetheless, very few metformin studies using mice have determined metformin concentrations and many effects of metform...

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Detalles Bibliográficos
Autores principales: Chaudhari, Kiran, Wang, Jianmei, Xu, Yong, Winters, Ali, Wang, Linshu, Dong, Xiaowei, Cheng, Eric Y., Liu, Ran, Yang, Shao-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289415/
https://www.ncbi.nlm.nih.gov/pubmed/32525922
http://dx.doi.org/10.1371/journal.pone.0234571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289415/
https://www.ncbi.nlm.nih.gov/pubmed/32525922
http://dx.doi.org/10.1371/journal.pone.0234571

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