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Determination of metformin bio-distribution by LC-MS/MS in mice treated with a clinically relevant paradigm
Metformin, an anti-diabetes drug, has been recently emerging as a potential “anti-aging” intervention based on its reported beneficial actions against aging in preclinical studies. Nonetheless, very few metformin studies using mice have determined metformin concentrations and many effects of metform...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289415/ https://www.ncbi.nlm.nih.gov/pubmed/32525922 http://dx.doi.org/10.1371/journal.pone.0234571 |