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DNA methylation patterns of LINE-1 and Alu for pre-symptomatic dementia in type 2 diabetes

The identification of early markers of dementia is important for higher-risk populations such as those with type 2 diabetes (T2D). Retrotransposons, including long interspersed nuclear element 1 (LINE-1) and Alu, comprise ~40% of the human genome. Although dysregulation of these retrotransposons can...

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Detalles Bibliográficos
Autores principales: Sae-Lee, Chanachai, Biasi, Julien De, Robinson, Natassia, Barrow, Timothy M., Mathers, John C., Koutsidis, Georgios, Byun, Hyang-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289438/
https://www.ncbi.nlm.nih.gov/pubmed/32525932
http://dx.doi.org/10.1371/journal.pone.0234578