Intimate functional interactions between TGS1 and the Smn complex revealed by an analysis of the Drosophila eye development

Trimethylguanosine synthase 1 (TGS1) is a conserved enzyme that mediates formation of the trimethylguanosine cap on several RNAs, including snRNAs and telomerase RNA. Previous studies have shown that TGS1 binds the Survival Motor Neuron (SMN) protein, whose deficiency causes spinal muscular atrophy...

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Detalles Bibliográficos
Autores principales: Maccallini, Paolo, Bavasso, Francesca, Scatolini, Livia, Bucciarelli, Elisabetta, Noviello, Gemma, Lisi, Veronica, Palumbo, Valeria, D'Angeli, Simone, Cacchione, Stefano, Cenci, Giovanni, Ciapponi, Laura, Wakefield, James G., Gatti, Maurizio, Raffa, Grazia Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289441/
https://www.ncbi.nlm.nih.gov/pubmed/32453722
http://dx.doi.org/10.1371/journal.pgen.1008815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289441/
https://www.ncbi.nlm.nih.gov/pubmed/32453722
http://dx.doi.org/10.1371/journal.pgen.1008815

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