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Intimate functional interactions between TGS1 and the Smn complex revealed by an analysis of the Drosophila eye development
Trimethylguanosine synthase 1 (TGS1) is a conserved enzyme that mediates formation of the trimethylguanosine cap on several RNAs, including snRNAs and telomerase RNA. Previous studies have shown that TGS1 binds the Survival Motor Neuron (SMN) protein, whose deficiency causes spinal muscular atrophy...
Autores principales: | Maccallini, Paolo, Bavasso, Francesca, Scatolini, Livia, Bucciarelli, Elisabetta, Noviello, Gemma, Lisi, Veronica, Palumbo, Valeria, D'Angeli, Simone, Cacchione, Stefano, Cenci, Giovanni, Ciapponi, Laura, Wakefield, James G., Gatti, Maurizio, Raffa, Grazia Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289441/ https://www.ncbi.nlm.nih.gov/pubmed/32453722 http://dx.doi.org/10.1371/journal.pgen.1008815 |
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