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Neonatal BCG Vaccination Reduces Interferon-γ Responsiveness to Heterologous Pathogens in Infants From a Randomized Controlled Trial

BACKGROUND: BCG vaccination has beneficial nonspecific (heterologous) effects that protect against nonmycobacterial infections. We have previously reported that BCG vaccination at birth alters in vitro cytokine responses to heterologous stimulants in the neonatal period. This study investigated hete...

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Detalles Bibliográficos
Autores principales: Freyne, Bridget, Messina, Nicole L, Donath, Susan, Germano, Susie, Bonnici, Rhian, Gardiner, Kaya, Casalaz, Dan, Robins-Browne, Roy M, Netea, Mihai G, Flanagan, Katie L, Kollmann, Toby, Curtis, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289544/
https://www.ncbi.nlm.nih.gov/pubmed/31990350
http://dx.doi.org/10.1093/infdis/jiaa030