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Measuring ligand-cell surface receptor affinities with axial line-scanning fluorescence correlation spectroscopy

Development and homeostasis of multicellular organisms is largely controlled by complex cell-cell signaling networks that rely on specific binding of secreted ligands to cell surface receptors. The Wnt signaling network, as an example, involves multiple ligands and receptors to elicit specific cellu...

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Detalles Bibliográficos
Autores principales: Eckert, Antonia Franziska, Gao, Peng, Wesslowski, Janine, Wang, Xianxian, Rath, Jasmijn, Nienhaus, Karin, Davidson, Gary, Nienhaus, Gerd Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289602/
https://www.ncbi.nlm.nih.gov/pubmed/32441251
http://dx.doi.org/10.7554/eLife.55286