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Measuring ligand-cell surface receptor affinities with axial line-scanning fluorescence correlation spectroscopy
Development and homeostasis of multicellular organisms is largely controlled by complex cell-cell signaling networks that rely on specific binding of secreted ligands to cell surface receptors. The Wnt signaling network, as an example, involves multiple ligands and receptors to elicit specific cellu...
Autores principales: | Eckert, Antonia Franziska, Gao, Peng, Wesslowski, Janine, Wang, Xianxian, Rath, Jasmijn, Nienhaus, Karin, Davidson, Gary, Nienhaus, Gerd Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289602/ https://www.ncbi.nlm.nih.gov/pubmed/32441251 http://dx.doi.org/10.7554/eLife.55286 |
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