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Zoledronic acid regulates the synthesis and secretion of IL-1β through Histone methylation in macrophages
Long-term administration of nitrogen-containing bisphosphonates increases the risk of detrimental side effects, such as bisphosphonate-related osteonecrosis of the jaw (BRONJ). BRONJ development is associated with inflammation, but its pathophysiology remains unknown. Here, we examined whether histo...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289826/ https://www.ncbi.nlm.nih.gov/pubmed/32566254 http://dx.doi.org/10.1038/s41420-020-0273-4 |