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N-terminal deletion of Swi3 created by the deletion of a dubious ORF YJL175W mitigates protein burden effect in S. cerevisiae

Extreme overproduction of gratuitous proteins can overload cellular protein production resources, leading to growth defects, a phenomenon known as the protein burden/cost effect. Genetic screening in the budding yeast Saccharomyces cerevisiae has isolated several dubious ORFs whose deletions mitigat...

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Detalles Bibliográficos
Autores principales: Saeki, Nozomu, Eguchi, Yuichi, Kintaka, Reiko, Makanae, Koji, Shichino, Yuichi, Iwasaki, Shintaro, Kanno, Manabu, Kimura, Nobutada, Moriya, Hisao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289859/
https://www.ncbi.nlm.nih.gov/pubmed/32528012
http://dx.doi.org/10.1038/s41598-020-66307-z