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Spatially-resolved metabolic profiling of living Drosophila in neurodegenerative conditions using (1)H magic angle spinning NMR

Drosophila flies are versatile animal models for the study of gene mutations in neuronal pathologies. Their small size allows performing in vivo Magic Angle Spinning (MAS) experiments to obtain high-resolution (1)H nuclear magnetic resonance (NMR) spectra. Here, we use spatially-resolved (1)H high-r...

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Detalles Bibliográficos
Autores principales: Yon, Maxime, Decoville, Martine, Sarou-Kanian, Vincent, Fayon, Franck, Birman, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289880/
https://www.ncbi.nlm.nih.gov/pubmed/32528106
http://dx.doi.org/10.1038/s41598-020-66218-z